Seroxat User Group

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Welcome to the Seroxat User Group Website

The Seroxat User Group was set up by UK patients using the GlaxoSmithKline medication, Seroxat, to provide support and advice to users of the medication, and to their families and friends.

We are a self-funding, non profit making group.

This web site contains information about the aims of the group, as well as research and articles on the effects of Seroxat.

SSRI CASE STUDY WANTED

A freelance journalist writing an article about the problem of withdrawal from SSRIs for the Daily Mail Good Health Section is looking for a case study.

Following new research proving conclusively that this a serious problem, particularly among young women.

A case study is needed under 40 years of age who has had a problem with coming off seroxat or another SSRI. If that's you then please email janice@seroxatusergroup.org.uk You will need to be interviewed, photographed and named and tell your story to bring this problem to life for readers and perhaps help many people who have given up hope of getting off this medication.

If you would like to discuss please get in touch asap. Thank you.

Protracted SSRI Withdrawal

If you have managed to withdraw from an SSRI and are still experiencing some side-effects or withdrawal symptoms, we'd like to hear from you.

SSRI Stories

If you are interested in researching news articles that mention anti-depressants then the following site is a comprehensive index of such articles: www.ssristories.com

Post SSRI Sexual Dysfunction (PSSD)

The MHRA is currently reviewing Post SSRI Sexual Dysfunction (PSSD), which is when the sexual dysfunction caused by taking antidepressants continues after the patient stops taking the drug. The online SSRISEX support group for people with the condition has over 2,100 members and numerous cases of PSSD have been documented in medical journals.

To report to the MHRA any sexual side effects caused by an SSRI that have continued once you have stopped taking the drug you can complete the online form here: http://yellowcard.mhra.gov.uk/. This will help to persuade the MHRA to address this serious health condition to help other patients.

What is Seroxat?

Seroxat is a second generation SSRI (Selective Serotonin Re-Uptake Inhibitor). SSRI's work by inhibiting serotonin re-uptake transporters thereby increasing serotonin levels in the brain. Serotonin is a chemical which affects the mood. By boosting that chemical the patient should feel better.

Manufactured by GlaxoSmithKline, Seroxat was first licensed in the UK on 11th December 1990 and was re-licensed on the 9th January 1998.

Seroxat's original licence was to treat episodes of mild to moderate depression. It is now licensed for the short term treatment of symptoms of depressive illness of types including:

Depression accompanied by anxiety.
Treatment of symptoms and prevention of relapse of obsessive compulsive disorder.
Treatment of symptoms and prevention of relapse of panic disorder with or without agoraphobia.

It is said to be useful for people who find social situations bring on these symptoms. However many patients using Seroxat have found that:

1. During treatment Seroxat can cause psychiatric problems that previously were not there and in some cases this had led to violent behaviour towards others and suicide.

2. The drug causes dependency (despite claims to the contrary) the withdrawal from which has caused the occurrence of new symptoms and an exacerbation of previous symptoms.

Seroxat was said by Smith Kline Beecham to be non-addictive (see patient information sheet). However patients world wide have described serious and long term side effects that make it very difficult to come off the drug after using it for as little as two days. Other complaints include the development of aggressive tendencies.

The Medicines and Healthcare Products Regulatory Agency (MHA) have compiled a Questions and Answers Document on Seroxat.

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DISCLAIMER: The material on this website is provided for information purposes only and is not a substitute for medical or psychiatric evaluation and treatment. The Seroxat User Group is not engaged in providing professional services or medical advice to the individual reader. Each individual's health is unique. All matters regarding health or a particular health situation should be supervised by a health care professional. The Seroxat User Group shall not be held responsible or liable for any harm or loss allegedly arising, directly or indirectly, from any information on this website. Medical advice should always be sought before discontinuing or changing medication.